Detalhe da pesquisa
1.
Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission.
Nature
; 609(7925): 101-108, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798029
2.
COVID-19 and the Motorcycle Taxi Sector in Sub-Saharan African Cities: A Key Stakeholders' Perspective.
Transp Res Rec
; 2677(4): 751-764, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38603305
3.
Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
J Biol Chem
; 294(23): 9029-9036, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31018963
4.
Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.
N Engl J Med
; 374(1): 54-61, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26698910
5.
The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.
J Biol Chem
; 292(38): 15705-15716, 2017 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28724631
6.
PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations.
Proc Natl Acad Sci U S A
; 112(11): 3493-8, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733882
7.
Conformational Studies and Atropisomerism Kinetics of the ALK Clinical Candidate Lorlatinib (PF-06463922) and Desmethyl Congeners.
Angew Chem Int Ed Engl
; 55(11): 3590-5, 2016 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880581
8.
Effect of water solvation on the lipophilicity of isomeric pyrimidine-carboxamides.
Bioorg Med Chem
; 23(13): 3408-13, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25963824
9.
Measurement of microenvironmental ozone concentrations in Durham, North Carolina, using a 2B Technologies 205 Federal Equivalent Method monitor and an interference-free 2B Technologies 211 monitor.
J Air Waste Manag Assoc
; 64(3): 360-71, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24701694
10.
Concentrations of mobile source air pollutants in urban microenvironments.
J Air Waste Manag Assoc
; 64(7): 743-58, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122949
11.
Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.
J Med Chem
; 66(7): 4888-4909, 2023 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940470
12.
The Choice of Osteosynthesis for Distal Radius Fractures: A Matter of Taste, Fracture Instability, or Patient-Related Factors? A Retrospective Study of Functional Outcome in 346 Distal Radius Fractures Operated With Percutaneous Wires or Volar Plate Fixation.
Hand (N Y)
; : 15589447221120850, 2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36168306
13.
LTK fusions: A new target emerges in non-small cell lung cancer.
Cancer Cell
; 40(1): 23-25, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35016028
14.
Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Nat Cancer
; 3(6): 710-722, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35726063
15.
Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission.
medRxiv
; 2022 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411350
16.
Atypical Presentations among Older Adults with COVID-19 Disease: A Need for Broadening the Differential Diagnosis.
Gerontol Geriatr Med
; 7: 2333721421999313, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33786339
17.
Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer.
Clin Cancer Res
; 27(10): 2899-2909, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33685866
18.
The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans.
Dev Cell
; 8(3): 321-30, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15737928
19.
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK.
Bioorg Med Chem Lett
; 20(24): 7429-34, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21036042
20.
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
Bioorg Med Chem Lett
; 20(20): 6096-9, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20817449